Containment of Arthropod Disease Vectors

Containment of arthropod disease vectors.

Effective containment of arthropod vectors of infectious diseases is necessary to prevent transmission of pathogens by released, infected vectors and to prevent vectors that escape from establishing populations that subsequently contribute to increased disease. Although rare, past releases illustrate what can go wrong and justify the need for guidelines that minimize risks. An overview of recom...

Arthropod Infestations and Vectors of Disease

Arthropod Vectors and Disease Transmission: Translational Aspects

Numerous diseases are transmitted by arthropod vectors, and for many of those diseases, effective vaccines are still not available. The contribution of the vector to the process of pathogen transmission is often overlooked, despite providing new avenues for combating vector-borne diseases, some of which could complement and significantly enhance ongoing efforts. To explore novel approaches to f...

Decoding the Ubiquitin-Mediated Pathway of Arthropod Disease Vectors

Protein regulation by ubiquitin has been extensively described in model organisms. However, characterization of the ubiquitin machinery in disease vectors remains mostly unknown. This fundamental gap in knowledge presents a concern because new therapeutics are needed to control vector-borne diseases, and targeting the ubiquitin machinery as a means for disease intervention has been already adop...

Risk Assessment for Arthropod Vectors

THE INTENT OF this section is to provide guidance and to establish a framework for selecting the appropriate arthropod containment level (facilities, equipment, and practices) that reduce risks of release and exposure of laboratory workers and the public to a vector and associated agents. “Risk” implies the probability that harm, injury, or disease will occur among laboratorians or the general ...